· Strain improvement

XFerm can provide and assist companies in solving the microbial production problems they often encounter

1.Increasing the productivity

2.Reducing the proportion of impurities

3.Improving the stability of strains

4.Reducing the viscosity of fermentation broth

5.Improving the adaptability and utilization of culture media

6.Shorten production cycle time

 

· Fermentation development

XFerm has more than 30 years of experience in fermentation research and development, mainly focusing on the evaluation of fermentor culture of target strains, development and optimization of fermentation processes, and small-scale trial production,pilot-scale production,commercial-scale production. We have researched a wide range of microorganisms, including bacteria, yeasts, Actinomycetes and fungi. 

· Downstream optimization

XFerm provide customized purification and recovery services, design small-scale processes (gram-level) and process optimization. Then we scales up (kg-level) and optimize the process to achieve industrial production.

XFerm provides customers with a recovery and purification method that can be scaled up for production by using the following process.

1.Extract Whole Broth

2.Partition by solvent

3.Resin adsorption and desorption

4.Evaporation and precipitation

5.Normal phase column purification

6.Reverse phase(C18) column purification

7.Crystallization

8.Vacuum drying